Well, just to re-establish what a huge dork I am, I have to say "Saying Goodbye" from the MTM.
For me, that song means more to me then almost any other Muppet song out there. I guess its sticking out in my head more these days, as my college friends are all graduating and moving to the big city! sniff. The lyrics just kind of resonate, and hit home right now (for those of you wondering, yeah, I've been crying all day - I think bawling or sobbing might be a more appropriate term - as my best friend left town today). Blah!
So that's my vote!